From: Planning a method for covariate adjustment in individually randomised trials: a practical guide
Outcome measure | Summary measure | Adjustment method | Model (variable modelled) | Treatment effect estimate (SE) |
---|---|---|---|---|
Any test (occurred in 35%) | Risk difference | Direct | Identity-link binomial (outcome) | - |
 |  | Standardisation | Logistic (outcome) | 0.258 (0.021)* |
 |  | IPTW | Logistic (treatment) | 0.259 (0.021) |
 | Log risk ratio | Direct | Poisson, robust SE (outcome) | 0.804 (0.069) |
 |  | Direct | Log-link binomial (outcome) | - |
 |  | Standardisation | Logistic (outcome) | 0.799 (0.075)* |
 |  | IPTW | Logistic (treatment) | 0.802 (0.075) |
Any diagnosis (occurred in 1.6%) | Risk difference | Direct | Identity-link binomial (outcome) | - |
 |  | Standardisation | Logistic (outcome) | - |
 |  | IPTW | Logistic (treatment) | 0.013 (0.006) |
 | Log risk ratio | Direct | Poisson, robust SE (outcome) | - |
 |  | Direct | Identity-link binomial (outcome) | - |
 |  | Standardisation | Logistic (outcome) | - |
 |  | IPTW | Logistic (treatment) | 0.866 (0.414) |