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Table 7 Appendix 2: Results of analyses of the GetTested trial targeting the all-randomised population. All models included main effects only. Link function is canonical unless otherwise specified. The dash symbol - means model did not converge, with reasons described in the text of Appendix 2

From: Planning a method for covariate adjustment in individually randomised trials: a practical guide

Outcome measure

Summary measure

Adjustment method

Model (variable modelled)

Treatment effect estimate (SE)

Any test (occurred in 35%)

Risk difference

Direct

Identity-link binomial (outcome)

-

  

Standardisation

Logistic (outcome)

0.258 (0.021)*

  

IPTW

Logistic (treatment)

0.259 (0.021)

 

Log risk ratio

Direct

Poisson, robust SE (outcome)

0.804 (0.069)

  

Direct

Log-link binomial (outcome)

-

  

Standardisation

Logistic (outcome)

0.799 (0.075)*

  

IPTW

Logistic (treatment)

0.802 (0.075)

Any diagnosis (occurred in 1.6%)

Risk difference

Direct

Identity-link binomial (outcome)

-

  

Standardisation

Logistic (outcome)

-

  

IPTW

Logistic (treatment)

0.013 (0.006)

 

Log risk ratio

Direct

Poisson, robust SE (outcome)

-

  

Direct

Identity-link binomial (outcome)

-

  

Standardisation

Logistic (outcome)

-

  

IPTW

Logistic (treatment)

0.866 (0.414)

  1. *Almost-all-randomised. Estimate was returned only after omitting four participants affected by collinearity