From: Planning a method for covariate adjustment in individually randomised trials: a practical guide
Outcome measure | Summary measure | Adjustment method | Model (variable modelled) | Treatment effect estimate (SE) |
---|---|---|---|---|
Any test (occurred in 35%) | Risk difference | Direct | Identity-link binomial (outcome) | - |
 |  | Standardisation | Logistic (outcome) | 0.260 (0.021) |
 |  | IPTW | Logistic (treatment) | 0.262 (0.021) |
 | Log risk ratio | Direct | Poisson, robust SE (outcome) | -* |
 |  | Direct | Log-link binomial (outcome) | 0.797 (0.075) |
 |  | Standardisation | Logistic (outcome) | 0.796 (0.074) |
 |  | IPTW | Logistic (treatment) | 0.806 (0.075) |
Any diagnosis (occurred in 1.6%) | Risk difference | Direct | Identity-link binomial (outcome) | - |
 |  | Standardisation | Logistic (outcome) | 0.015 (0.006) |
 |  | IPTW | Logistic (treatment) | 0.013 (0.006) |
 | Log risk ratio | Direct | Poisson, robust SE (outcome) | 0.972 (0.433) |
 |  | Direct | Log-link binomial (outcome) | 0.915 (0.412) |
 |  | Standardisation | Logistic (outcome) | 0.959 (0.412) |
 |  | IPTW | Logistic (treatment) | 0.855 (0.412) |