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Table 1 Statistical power analysis

From: Transfer of FRozen Encapsulated multi-donor Stool filtrate for active ulcerative Colitis (FRESCO): study protocol for a prospective, multicenter, double-blind, randomized, controlled trial

True rates [%] Sample size per group (including dropouts)a Power for the respective test setting [%]
πFMT πFMFT πPlacebo Global testb FMT and FMFT vs. placebo FMT or FMFT vs. placebo
30 30 5 58 93 98 92
30 40 10 58 92 95 69 rsp 95
40 40 10 58 96 99 95
  1. aResulting in a total sample size would be 3 × 58 = 174, 3 × 93 = 279, and 3 × 50 = 150 patients to be randomized
  2. bThe increased power (i.e., a power larger than 80%) results from the inclusion of dropouts in the analysis