Effect of perioperative cognitive behavioural therapy on chronic post-surgical pain among breast cancer patients with high pain catastrophising characteristics: protocol for a double-blinded randomised controlled trial

Table 2 Time schedule for various points during study period

		Study period
	Enrolment	Allocation	Post-allocation						Primary and secondary outcomes
Time point	-t₁	0	14 days pre-op	7 days pre- op	Intra-operative	24-48 h post-op	7 days post- op	14 days post- op	30 days	90 days
Enrolment:
Eligibility screen (inclusion and exclusion criteria)	X
Informed consent	X
Baseline PCS (> 24: eligible to enrol)	X
Randomisation		X
Interventions:
CBT session group			X	X			X	X
PEM session group			X	X			X	X
Assessments:
Patient demographics and characteristics	X
Intraoperative data					X
BPI		X							X	X
QoR-15						X
PCS	x								X	X
HADS									X	X

PCS Pain Catastrophising Scale, CBT cognitive behavioural therapy, PEM pain education and mindfulness, BPI Brief Pain Inventory score, QoR-15 Quality of Recovery-15 score, HADS Hospital Anxiety and Depression Scale

ISSN: 1745-6215