Low-dose corticosteroid therapy for cardiogenic shock in adults (COCCA): study protocol for a randomized controlled trial

Table 2 Enrollment, intervention, and evaluations

Time points	ICU admission to enrollment	Experimental period							Early follow-up (D7 or ICU discharge)	Follow-up	Close out
Time points	D0	D1	D2	D3	D4	D5	D6	D7	Dx	D28	D90 + 20 days
Enrollment
Eligibility screen	•
Informed consent	•
Randomization	•
Intervention
Physical examination	•	•	•	•	•	•	•	•
Biology exams	•	•	•	•	•	•	•	•
Echocardiography	•		•						•
Corticotropin stimulation test	•
Treatment		•	•	•	•	•	•	•
Assessments
Collection of data on the occurrence of primary endpoint									•
Collection of data on the occurrence of secondary endpoints									•	•	•
Serious adverse events		•	•	•	•	•	•	•	•	•	•

ISSN: 1745-6215