Study period | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Enrollment | Allocation | Post allocation | ||||||||||
Time point | Preoperative | 0 d | surgery | 2 h | 4 h | 8 h | 12 h | 16 h | 20 h | 1d | 2d | Discharge |
Enrollment | ||||||||||||
Eligibility screen | X | |||||||||||
Informed consent | X | |||||||||||
Allocation | X | |||||||||||
Interventions | ||||||||||||
Scalp nerve blocks with bupivacaine | X | |||||||||||
Scalp nerve blocks with bupivacaine plus 4 mg dexamethasone | X | |||||||||||
Assessments | ||||||||||||
Baseline variables | X | X | X | |||||||||
Intraoperative data | X | |||||||||||
The duration of analgesia | X | X | ||||||||||
NRS score | X | X | X | X | X | X | X | X | ||||
GCS score | X | X | X | X | X | X | X | X | ||||
PSS | X | X | X | X | X | X | X | X | ||||
LOS | X | |||||||||||
PONV | X | X | X | X | X | X | X | X | ||||
Bradycardia | X | X | X | X | X | X | X | X | ||||
Hypotension | X | X | X | X | X | X | X | X | ||||
Emergence delirium | X | X | X | X | X | X | X | X | ||||
HR and MAP | X | |||||||||||
Occurrence of AEs and SAEs | X | X | X | X | X | X | X | X | X | X |