PRagMatic Pediatric Trial of Balanced vs nOrmaL Saline FlUid in Sepsis: study protocol for the PRoMPT BOLUS randomized interventional trial

Table 4 Fluid administration

Characteristic	0.9% saline	Balanced/buffered fluid
	(n = )	(n = )
Number of crystalloid fluid boluses, median (IQR)
Total^a
Prior to randomization
During intervention phase
Crystalloid volume administered (mL/kg), median (IQR)
Total fluid (bolus and maintenance)^a
Any crystalloid
0.9% saline
Balanced/buffered fluid
Bolus fluid only
Prior to randomization
During intervention phase
0.9% saline
Balanced/buffered fluid
Maintenance fluid only
Any crystalloid
0.9% saline
Balanced/buffered fluid
Other
Colloid volume administered (mL/kg), median (IQR)
Albumin 4%/5%
Other
Blood product volume administered (mL/kg), median (IQR)
Red blood cells
Platelets
Plasma or cryoprecipitate
Other
Fluid volume categories^a, n (%)
Total crystalloid (bolus and maintenance)
<60 mL/kg
60–100 mL/kg
>100 mL/kg
Bolus fluid only
<60 mL/kg
60–100 mL/kg
>100 mL/kg
Protocol Adherence
Received ≥75% of total crystalloid as randomized fluid type during intervention phase, n (%)

^aIncludes fluid administered prior to randomization and during the intervention phase

ISSN: 1745-6215