Characteristic | 0.9% saline | Balanced/buffered fluid | Difference (95% CI) |
---|---|---|---|
(n = ) | (n = ) | ||
Number of crystalloid fluid boluses, median (IQR) | |||
Totala | |||
Prior to randomization | |||
During intervention phase | |||
Crystalloid volume administered (mL/kg), median (IQR) | |||
Total fluid (bolus and maintenance)a | |||
Any crystalloid | |||
0.9% saline | |||
Balanced/buffered fluid | |||
Bolus fluid only | |||
Prior to randomization | |||
During intervention phase | |||
0.9% saline | |||
Balanced/buffered fluid | |||
Maintenance fluid only | |||
Any crystalloid | |||
0.9% saline | |||
Balanced/buffered fluid | |||
Other | |||
Colloid volume administered (mL/kg), median (IQR) | |||
Albumin 4%/5% | |||
Other | |||
Blood product volume administered (mL/kg), median (IQR) | |||
Red blood cells | |||
Platelets | |||
Plasma or cryoprecipitate | |||
Other | |||
Fluid volume categoriesa, n (%) | |||
Total crystalloid (bolus and maintenance) | |||
<60 mL/kg | |||
60–100 mL/kg | |||
>100 mL/kg | |||
Bolus fluid only | |||
<60 mL/kg | |||
60–100 mL/kg | |||
>100 mL/kg | |||
Protocol Adherence | |||
Received ≥75% of total crystalloid as randomized fluid type during intervention phase, n (%) |