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Table 4 Fluid administration

From: PRagMatic Pediatric Trial of Balanced vs nOrmaL Saline FlUid in Sepsis: study protocol for the PRoMPT BOLUS randomized interventional trial

Characteristic 0.9% saline Balanced/buffered fluid Difference (95% CI)
  (n = ) (n = )  
Number of crystalloid fluid boluses, median (IQR)    
 Totala    
 Prior to randomization    
 During intervention phase    
Crystalloid volume administered (mL/kg), median (IQR)    
 Total fluid (bolus and maintenance)a    
  Any crystalloid    
  0.9% saline    
  Balanced/buffered fluid    
 Bolus fluid only    
  Prior to randomization    
  During intervention phase    
  0.9% saline    
  Balanced/buffered fluid    
 Maintenance fluid only    
  Any crystalloid    
  0.9% saline    
  Balanced/buffered fluid    
  Other    
Colloid volume administered (mL/kg), median (IQR)    
 Albumin 4%/5%    
 Other    
Blood product volume administered (mL/kg), median (IQR)    
 Red blood cells    
 Platelets    
 Plasma or cryoprecipitate    
 Other    
Fluid volume categoriesa, n (%)    
 Total crystalloid (bolus and maintenance)    
  <60 mL/kg    
  60–100 mL/kg    
  >100 mL/kg    
 Bolus fluid only    
  <60 mL/kg    
  60–100 mL/kg    
  >100 mL/kg    
Protocol Adherence    
 Received ≥75% of total crystalloid as randomized fluid type during intervention phase, n (%)    
  1. aIncludes fluid administered prior to randomization and during the intervention phase