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Primary outcomes
|
|
Nutrition status
|
Body weight, kg
|
Change from baseline (V1) at1 day prior to discharge (V3); change from 1 day prior to discharge (V3) at 30 days after surgery (V4); change from 1 day prior to discharge (V3) at 90 days after surgery (V5)
|
Mean
|
|
BMI, kg/m2
|
|
Serum albumin, g/L
|
|
Serum prealbumin, mg/L
|
|
Secondary outcomes
|
|
Nutrition status
|
Handgrip strength, kgF
|
Change from baseline (V1) at 1 day prior to discharge (V3); change from 1 day prior to discharge (V3) at 30 days after surgery (V4); change from 1 day prior to discharge (V3) at 90 days after surgery (V5)
|
Mean
|
|
Muscle mass, kg
|
|
Fat mass, kg
|
|
Serum transferrin, g/L
|
|
Haemoglobin, g/dL
|
|
Inflammation
|
High-sensitivity C-reactive Protein (hs-CRP), mg/L
|
Mean
|
|
Interleukin-6 (IL-6), pg/ml
|
|
Salivary cortisol, μg/dL
|
|
Dietary intake
|
Energy intake, kcal/d
|
Mean
|
|
Protein intake, g/d
|
|
Sleep quality
|
Pittsburgh Sleep Quality Index (PSQI) score
|
Median
|
|
Postoperative complications
|
Postoperative complications
|
Frequency of postoperative complications at discharge (V3), at 30 days after surgery (V4), and 90 days after surgery (V5)
|
Median
|
|
Length of hospital stay
|
Number of days of hospitalisation from admission (V1) to 1 day before discharge (V3)
|
Median
|
