Efficacy of expressive helping in adult hematologic cancer patients undergoing stem cell transplant: protocol for the Writing for Insight, Strength, and Ease (WISE) study’s two-arm randomized controlled trial

Table 2 Summary of patient-completed study assessments

Timing of assessment		Pre-transplant baseline	7 days post-transplant	14 days post-transplant	Intervention period	1 week post-intervention	3 months post-intervention	6 months post-intervention	12 months post-intervention
Variable	Measure	Time 1	Time 2	Time 3	Writing Days	Time 4	Time 5	Time 6	Time 7
Primary outcome
Symptom severity	MDASI-BMT	X	X	X		X	X	X	X
Secondary outcomes
Depressive symptoms	CES-D	X	X	X		X	X	X	X
Anxiety	GAD-7	X	X	X		X	X	X	X
Anxiety	IES	X	X	X		X	X	X	X
Health-related quality of life	PROMIS Global Health	X				X	X	X	X
Fatigue	FACIT-Fatigue	X	X	X		X	X	X	X
Potential covariates
Demographics		X
Sleep quality	Pittsburgh Sleep Index	X				X	X	X	X
Writing day measures
Emotional and physiological arousal pre- and post-writing	Standard items				X
Post-writing manipulation check	Standard items				X

MDASI MD Anderson Symptom Inventory-Bone Marrow Transplant, CES-D Center for Epidemiologic Studies Depression Scale, GAD-7 7-item Generalized Anxiety Disorder, IES Impact of Events Scale, PROMIS Patient Reported Outcomes Measurement Information System, FACIT Functional Assessment of Chronic Illness Therapy

ISSN: 1745-6215