Table 1 Inclusion and exclusion criteria of DigiSep-trial

Inclusion criteria

 Age ≥ 18 years

 Informed consent

 Sepsis or septic shock (with an onset ≤ 24 h)

Exclusion criteria

 Age < 18 years

 Refusal to give consent

 Patient will probably be discharged from the ICU/IMC within the first 72 h following inclusion

 Palliative treatment intent

 Clinician is not committed to aggressive treatment

 Death is deemed imminent and inevitable

 Patients who had previously been included but are readmitted to the ICU/IMC during the same hospitalization will not be included a second time.