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Table 2 Liver function-related parameters and serum lipid levels before and 12 weeks after consuming FRVE

From: Effect of fermented Rhus verniciflua stokes extract on liver function parameters in healthy Korean adults: a double-blind randomized controlled trial

 

Group (total = 52)

Control (n = 25)

FRVE (n = 27)

 

0 weeks

12 weeks

pa

0 weeks

12 weeks

pa

pb

AST (IU/L)*

20.48 (± 1.44)

19.88 (± 1.24)

0.778

20.15 (± 1.12)

20.85 (±1.75)

0.836

 

change

−0.60 (± 1.38)

 

0.70 (±0.96)

 

0.436

ALT (IU/L)*

17.67 (± 2.71)

17.25 (± 1.96)

0.500

16.63 (± 1.62)

16.89 (±1.90)

0.928

 

change

−0.42 (± 1.88)

 

0.26 (±1.31)

 

0.765

AST/ALT ratio

1.44 (± 0.10)

1.36 (± 0.10)

0.095

1.40 (± 0.09)

1.38 (±0.08)

0.832

 

change

−0.09 (± 0.05)

 

−0.02 (±0.09)

 

0.523

GGT (mg/dL)*

18.32 (± 2.02)

17.48 (± 1.99)

0.241

21.59 (± 3.06)

19.44 (±2.88)

0.063

 

change

−0.84 (± 0.70)

 

−2.15 (±1.11)

 

0.331

ALP (IU/L)

64.56 (± 2.92)

63.08 (± 2.50)

0.289

66.00 (± 4.21)

65.31 (±4.28)

0.608

 

change

−1.48 (± 1.36)

 

−0.63 (±1.21)

 

0.642

TC (mg/dL)

190.84 (± 5.07)

187.20 (± 4.93)

0.231

179.44 (± 5.69)

176.56 (±5.89)

0.377

 

change

−3.64 (± 2.96)

 

−2.89 (±3.22)

 

0.865

TG (mg/dL)*

125.76(± 23.55)

97.68 (± 11.12)

0.073

138.74 (± 22.23)

110.70 (±17.26)

0.046

 

change

−28.08 (± 13.64)

 

−28.04 (±14.20)

 

0.998

HDL-C (mg/dL)

60.44 (± 2.93)

62.32 (± 2.44)

0.184

62.59 (± 3.48)

62.52 (±3.23)

0.957

 

change

1.88 (± 1.38)

 

−0.07 (±1.37)

 

0.320

LDL-C (mg/dL)

105.25 (± 5.39)

105.34 (± 5.01)

0.976

92.26 (± 5.61)

95.73 (±5.71)

0.306

 

change

0.10 (± 3.21)

 

3.47 (±3.32)

 

0.469

  1. Data are presented as mean ± SE
  2. AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, GGT ɣ-glutamyl transferase, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides
  3. *Tested using logarithmic transformation
  4. ap-values were calculated using paired t-test when comparing the baseline values (0 weeks)
  5. bp-values were calculated using the independent t-test comparing the “change” values