From: Estimands in published protocols of randomised trials: urgent improvement needed
Question* | Trials—n/N (%) |
---|---|
Non-adherence/discontinuation | |
 Applicable | 50/50 (100%) |
 Stated | 0 (0%) |
 Inferable | 34 (68%) |
 Not inferable | 16 (32%) |
Treatment switching | |
 Applicable | 3/50 (6%) |
 Stated | 0/3 (0%) |
 Inferable | 3/3 (100%) |
 Not inferable | 0/3 (0%) |
Mortality | |
 Applicable | 20/50 (40%) |
 Stated | 0/20 (0%) |
 Inferable | 4/20 (20%) |
 Not inferable | 16/20 (80%) |
Other intercurrent events | |
 Applicable | 10/50 (20%) |
 All stated | 0/10 (0%) |
 All inferable | 7/10 (70%) |
 Not all inferable | 3/10 (30%) |