The impact of deep versus standard neuromuscular block on intraoperative safety during laparoscopic surgery: an international multicenter randomized controlled double-blind strategy trial — EURO-RELAX TRIAL

Table 2 Schematic schedule of enrolment, interventions, and study outcomes

		Study period
	Enrolment	Allocation	Surgery	Follow-up			Close-out
*Timeframe*	*− 14 days*	*OR day*	*OR day*	*+ 1 day*	*+ 2 days*	*+ 3 days*	*+ 30 days*
Eligibility screening	X
Informed consent	X
Randomization		X
Intervention
Standard or deep NMB			X
Primary, secondary, and postoperative outcomes
ClassIntra Grade® [14]			X
L-SRS [6, 23]			X
QoR-40 [16, 17]	X			X	X
SF-36 [15]	X						X
Clavien-Dindo and CCI [18, 19]				X	X	X	X
Readmission rate							X
NRS and administered analgesics	X		X	X	X	X

CCI Comprehensive Complication Index, L-SRS Leiden Surgical Rating Scale, NMB neuromuscular block, NRS Numeric Rating Scale, QoR-40 Quality of recovery, SF-36 Short-Form 36

ISSN: 1745-6215