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Table 2 Composition and action of Guizhi-Shaoyao-Zhimu decoction in Chinese herbal medicine

From: Observation of the curative effect of Guizhi-Shaoyao-Zhimu decoction combined with methotrexate in the treatment of early rheumatoid arthritis based on ultrasonic evaluation: study protocol of a randomized, double-blind, controlled clinical trial

Ingredient Granule dose Action (TCM)
Cinnamomum cassia (guizhi) 4.5 g 1. Relieving exterior syndrome by diaphoresis
2. Harmonizing yingfen and weifen
3. Warming the channel and activating blood circulation warming the meridian to relieve pain
Radix of Paeonia lactiflora (Shaoyao) 4.5 g 1. Nourishing the blood
2. Reducing yin
3. Soothing the liver
4. Relieving pain stabilizing yin and yang in the liver
Radix and Rhizoma of Glycyrrhiza uralensis (gancao) 3 g 1. Clearing heat and removing toxicity
2. Invigorating spleen and supplementing qi moderating the property of herbs
Rhizoma of Anemarrhena asphodeloides (Zhimu) 4.5 g 1. Clearing heat-fire nourishing yin for moistening dryness
Rhizoma of Atractylodes macrocephala (Baizhu) 4.5 g 1. Invigorating the spleen replenish qi
Rhizoma of Zingiber officinale (Shengjiang) 3 g Resolve the exterior and dissipate cold
Radix of Saposhnikovia divaricata (Fangfeng) 4.5 g 1. Expelling wind to relieve superficies
2. Removing dampness to relieve pain
Processed lateralis Radix of Aconitum carmichaeli (Paofuzhi) 1.5 g 1. Tonifying fire and helping yang
2. Dispelling cold and removing dampness