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Table 4 Outcomes and covariates

From: BiCyCLE NMES—neuromuscular electrical stimulation in the perioperative treatment of sarcopenia and myosteatosis in advanced rectal cancer patients: design and methodology of a phase II randomised controlled trial

Demographics

o Patient age

o Patent birth year

o Patient gender

o Patient ethnicity coding

o Weight

o Height

o Body mass index

Outcome measures

o 90-day post-operative complications (Clavien-Dindo classification (18))

o Disease outcomes including 30-day survival

o Death / recurrence / disease-free survival

o Patient compliance diary data

o Device usage

Disease

o ASA grade (American College of Anaesthesiology) physical status

o Past medical history (other or previous illnesses and surgery)

Body composition parameters

o CT body composition at the level of the L3 vertebra

o Bio-impedance analysis

o Anthropometric measurements

Cancer-specific characteristics

o Type of cancer (primary/recurrent cancer, location and subtype on histology)

o Grade of cancer

o Stage of cancer

Inflammatory markers

o Serum C-reactive protein

o White cell count

o Serum albumin

o Platelet count

Treatment factors

o Details of surgery

o Chemotherapy

o Radiotherapy

Patient-specific and functional outcomes

o Quality of life

- ED-5Q-5L

- EORTC QLQ – CR29

o Patient satisfaction