Groups | Interventions |
---|---|
Experimental group | Colchicine plus symptomatic treatment (paracetamol) Patients in this arm will receive study medication colchicine 0.5 mg orally (PO) twice, daily for the first 3 days and then once daily for the last 18 days. If a dose is missed, it should not be replaced. All patients should also receive the best symptomatic treatment (mainly paracetamol), based on clinical practice. |
Control group | Symptomatic treatment Symptomatic treatment (paracetamol or best symptomatic treatment) based on doctor recommendations. |