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Table 2 Parameter setting for binomial outcomes (log odds scale)

From: Power and sample size calculation for stepped-wedge designs with discrete outcomes

 

Simulation

EPT Trial

LIRE Trial

# of sequence

3

4

5

# of time period (Nt)

4

5

6

# of cluster per sequence

4, 8, 12

6

20

# of pcp per cluster

NA

NA

35

Cluster size

20, 50, 100

?

?

Prevalence (roughly)

0.03, 0.12, 0.43

0.08

0.19

Fixed time effect βtime

(0.1, 0.1, 0.1)

(−0.008, −0.08, -0.17, −0.11)

−0.124

Effect size for the intervention βp

0.2

−0.3

−0.055

SD of random cluster effect

0.05

0.2

0.011

SD of random treatment effect

0.05, 0.1

NA

0.0054

SD of random time effect

0.05, 0.1

0.12

NA

SD of random cluster (pcp) effect

NA

NA

0.0015

  1. *The cluster for LIRE Trial represents clinic, the random treatment effect is at clinic level, and time is modeled as a continuous variable
  2. **SD stands for standard deviation