Table 3 Research flowchart

−3d~0d

0d

4w

8w

12w

Enrolment

Sign informed consent

✔

Inclusion and exclusion criteria

✔

Demographic data

✔

Medical history and treatment history

✔

Basic data collection

✔

Outcome assessment

Frequency of atrial fibrillation

✔

✔

✔

✔

ECG and Holter

✔

✔

✔

✔

Ultrasonic cardiogram

✔

✔

✔

✔

TCM clinical syndrome integral

✔

✔

✔

✔

Rate of increase and decrease of anti-arrhythmia western medicine

✔

✔

✔

✔

NT-proBNP

✔

✔

Hamilton Anxiety Scale

✔

✔

✔

✔

Hamilton Depression Scale

✔

✔

✔

✔

SF-36

✔

✔

✔

✔

PVO

✔

✔

✔

✔

Anaerobic threshold

✔

✔

✔

✔

Safety assessment

Physical examination

✔

✔

✔

✔

Blood routine examination

✔

✔

Urine routine and urinary sediment

✔

✔

Liver function

✔

✔

Renal function

✔

✔

Blood lipid

✔

✔

GLU

✔

✔

INR

✔

✔

CHA2DS2-VAS

✔

✔

HAS-BCED

✔

✔

Other information

Randomization

✔

Hemorrhage

✔

✔

✔

✔

Readmission

✔

✔

✔

✔