Skip to main content

Table 3 Pre-specified decision rules for the CLARITY trial. Details about how these probabilities are evaluated/approximated are available in the statistical analysis plan

From: Protocol for the Controlled evaLuation of Angiotensin Receptor blockers for COVID-19 respIraTorY disease (CLARITY): a randomised controlled trial

Reason for stopping Posterior probability Decision rule
Effectiveness Pr(OR < log(1.00)) > 0.975 > 0.95
Futility Pr(OR < log(1.00)) > 0.975 < 0.02