Table 3 Pre-specified decision rules for the CLARITY trial. Details about how these probabilities are evaluated/approximated are available in the statistical analysis plan
Reason for stopping | Posterior probability | Decision rule |
|---|---|---|
Effectiveness | Pr(OR < log(1.00)) > 0.975 | > 0.95 |
Futility | Pr(OR < log(1.00)) > 0.975 | < 0.02 |