Effect of GreenshellTM mussel on osteoarthritis biomarkers and inflammation in healthy postmenopausal women: a study protocol for a randomized double-blind placebo-controlled trial

Table 1 The schedule for enrollment, the interventions, and the assessments

	Study period
	Enrollment	Allocation	Post-allocation
Timepoint	-t₂	-t₁	T₀	T₆	T₁₂
Enrollment:
Eligibility screen	X
Informed consent	X
Allocation		X
Washout period		X
Intervention:
Administration of GSM supplement and placebo			X	X	X
Assessments:
Blood and urine sample collection			X	X	X
Pain assessment; VAS and KOOS			X		X
Body composition, DXA scan			X		X
Food intake; 3-day food record				X
Compliance				X	X

ISSN: 1745-6215