Fig. 2

Study schedule data collection showing time points for enrollment and assessment. The informed consent and examination will be conducted after recruitment. After that, we will randomly match PSD patients into two groups, one group will receive Tuina with herbal ointment treatment and the other will receive only herbal ointment. Clinical results will be performed at four time points, including the baseline, at the end of the intervention 2 weeks, and during the 1 month and 3 months of follow-up. During the study, adverse events will be recorded on the case report form. HAMD Hamilton Rating Scale for Depression, TMS Transcranial Magnetic Stimulation, MPQ McGill pain questionnaire, SF-36 36-item Short-Form Health Survey, TESS Treatment Emergent Symptom Scale. W-1 screening before enrollment; W0 baseline assessment; W2 assessment after the 10th treatment, which is in the second week; W4 and W12 are the follow-up period of the 4th and 12th weeks after the first treatment