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Fig. 3 | Trials

Fig. 3

From: Microbial Interventions to Control and Reduce Blood Pressure in Australia (MICRoBIA): rationale and design of a double-blinded randomised cross-over placebo controlled trial

Fig. 3

Collection and analyses of the gut microbiome. Following measurement of blood pressure (office and 24 h ambulatory blood pressure monitoring) and pulse wave velocity, participants collect a faecal sample. The DNA is then extracted; library targeting the 16S bacterial gene or whole-metagenome is prepared and sequenced. Bioinformatics analyses are used to determine taxonomic differences (before/after placebo and intervention), alpha diversity (i.e. within sample diversity), and beta diversity (i.e. between sample diversity). Plots are only representative

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