Table 1 A schematic overview of the study design. Definition of timepoints: t₁: Within 36 h after admission the ED, t_a: Immediately after data collection upon enrollment has ended, t_GFR: During hospitalization or up to 2 weeks after discharge, t₂: 8 weeks after discharge, t₃: 16 weeks after discharge, t_1y: 1 year after discharge. Abbreviations: GFR glomerular filtration rate, MULTI multidisciplinary, NUT nutritional, MED medication

 Eligibility screening

x

 Informed consent

x

 Allocation

x

 Nutritional screening

x

Interventions

 MULTI-NUT-MED intervention

x

x

 MED intervention

x

 Descriptive variables

x

Primary outcomes

 Health related quality of life

x

x

x

x

 Medication appropriateness

x

x

x

x

 Kidney Function

x

 Underutilization of medication

x

x

x

 Energy and protein intake

During admission

x

x

 Mobility

x

x

x

 Activities of daily living

x

x

x

 Well-being

x

x

x

 Frailty

x

x

x

 Anthropometry

x

x

x

 Blood pressure and heart rate

x

x

x

 Mortality

x

x

 Cognition

x

x

x

 Depression

x

x

x

 Blood samples

x

x

x

x

 Health economy

x

x

x

 Gene variations

x

 Body composition

x

x

x

x

 Nutritional status

x

x

x

 Intestinal microbiota

x

x

x