Time point | Study period | ||||||
---|---|---|---|---|---|---|---|
Enrolment | Allocation | Post-allocation | |||||
1 week pre | 0 | 1 month | 3 months | 6 months | 12 months | 24 months | |
Enrollment | |||||||
Eligibility screen | X | ||||||
Informed consent | X | ||||||
Allocation | X | ||||||
Interventions | |||||||
Standard care | X | X | X | X | X | ||
Standard care plus fosinopril | X | X | X | X | X | ||
Assessments | |||||||
Demographics | X | ||||||
Physical examinations | X | X | X | X | X | X | |
Medical history | X | X | X | X | X | X | |
Laboratory tests | X | X | X | X | X | X | |
NYHA class | X | X | X | X | X | X | |
Transthoracic echocardiography | X | X | X | X | X | X | |
CMR | X | X | |||||
KCCQ | X | X | X | X | X | X | |
6-min walk test | X | X | X | X | X | X | |
Adverse events | X | X | X | X | X |