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Table 1 AVATAR2 measures

From: Optimising AVATAR therapy for people who hear distressing voices: study protocol for the AVATAR2 multi-centre randomised controlled trial

  Measure Time-pointa
Distress, frequency and severity of voices outcome measures Psychotic Symptom Rating Scales – Auditory Hallucinations – a dimensional measure of hallucinations- [27]. Includes Distress dimension (primary outcome), Total score (secondary outcome), and Frequency dimension (secondary outcome) [28].
Hallucinations Remission Score
1, 2, 3
Other voices outcome measures Beliefs about Voices Revised (BAVQ-R) [30]
Voices acceptance and action scale (VAAS) [31]
First item (power) from the Voice Power Differential Scale [32]
1, 2, 3
Experience sampling methodology AVATAR2 ESM Questionnaire [33] 1,2,3
AVATAR2 ESM Debrief Questionnaire e.g. [34] 1,2,3
Other secondary outcome measures Mood: Beck Depression Inventory-II [35] 1, 2, 3
Anxiety: Depression Anxiety and Stress Scales (DASS-21) [36] 1,2,3
Quality of Life: Warwick-Edinburgh Mental Well-being Scale [37] 1, 2, 3
Delusions: Psychotic Symptoms Rating Scale (PSYRATS-DEL) [27] 1, 2, 3
Service User Led Outcome Measure: Choice of Outcome in CBT for Psychosis (CHOICE) Short Form [38] 1,2,3
Trauma related symptoms – International Trauma Questionnaire (ITQ) [39] 1, 2
Health economic outcome measures Service use and costs: costs of the intervention (based on staff time, overheads and equipment) and the costs of other key health and social care services calculated using the [40]. 1, 2, 3
EQ-5D-5L [41] to measure QALYs 1, 2, 3
Baseline clinical characteristics Voice Characterisation Checklist: Assesses the complexity in characterisation of the dominant voice. Rated as more vs. less highly characterised based on presence/absence of ascribed identity (e.g. known, name), physical characteristics (e.g. age, gender, accent) and psychosocial characteristics (e.g. intentions, thoughts, relationships)-see [19]. Including two items from the Voice Phenomenology Interview [42]. 1
Fearful Attachment Style Item from Relationships Questionnaire [43]. 1
Patient perceived trauma-voice links - Trauma Voice Associations Questionnaire (TVAQ) [44]. 1
Trauma history - Mini-Trauma And Life Events (TALE) checklist [45] 1
Clinical Assessment Interview for Negative Symptoms (CAINS) [46] 1
Identification of positive symptoms – Initial items from the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) 2.1 [47] 1
Detailed assessment of positive symptoms - Scale for the Assessment of Positive Symptoms [48] 1
COVID-19 Impact COVID-19 Context Questionnaire to assess individual circumstances during pandemic and change in voice experiences. 1, 2, 3
  1. a1 = baseline, 2 = 16 weeks post-randomisation, 3 = 28 weeks post-randomisation