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Table 1 AVATAR2 measures

From: Optimising AVATAR therapy for people who hear distressing voices: study protocol for the AVATAR2 multi-centre randomised controlled trial

 

Measure

Time-pointa

Distress, frequency and severity of voices outcome measures

Psychotic Symptom Rating Scales – Auditory Hallucinations – a dimensional measure of hallucinations- [27]. Includes Distress dimension (primary outcome), Total score (secondary outcome), and Frequency dimension (secondary outcome) [28].

Hallucinations Remission Score

Screening,

1, 2, 3

Other voices outcome measures

Beliefs about Voices Revised (BAVQ-R) [30]

Voices acceptance and action scale (VAAS) [31]

First item (power) from the Voice Power Differential Scale [32]

1, 2, 3

Experience sampling methodology

AVATAR2 ESM Questionnaire [33]

1,2,3

AVATAR2 ESM Debrief Questionnaire e.g. [34]

1,2,3

Other secondary outcome measures

Mood: Beck Depression Inventory-II [35]

1, 2, 3

Anxiety: Depression Anxiety and Stress Scales (DASS-21) [36]

1,2,3

Quality of Life: Warwick-Edinburgh Mental Well-being Scale [37]

1, 2, 3

Delusions: Psychotic Symptoms Rating Scale (PSYRATS-DEL) [27]

1, 2, 3

Service User Led Outcome Measure: Choice of Outcome in CBT for Psychosis (CHOICE) Short Form [38]

1,2,3

Trauma related symptoms – International Trauma Questionnaire (ITQ) [39]

1, 2

Health economic outcome measures

Service use and costs: costs of the intervention (based on staff time, overheads and equipment) and the costs of other key health and social care services calculated using the [40].

1, 2, 3

EQ-5D-5L [41] to measure QALYs

1, 2, 3

Baseline clinical characteristics

Voice Characterisation Checklist: Assesses the complexity in characterisation of the dominant voice. Rated as more vs. less highly characterised based on presence/absence of ascribed identity (e.g. known, name), physical characteristics (e.g. age, gender, accent) and psychosocial characteristics (e.g. intentions, thoughts, relationships)-see [19]. Including two items from the Voice Phenomenology Interview [42].

1

Fearful Attachment Style Item from Relationships Questionnaire [43].

1

Patient perceived trauma-voice links - Trauma Voice Associations Questionnaire (TVAQ) [44].

1

Trauma history - Mini-Trauma And Life Events (TALE) checklist [45]

1

Clinical Assessment Interview for Negative Symptoms (CAINS) [46]

1

Identification of positive symptoms – Initial items from the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) 2.1 [47]

1

Detailed assessment of positive symptoms - Scale for the Assessment of Positive Symptoms [48]

1

COVID-19 Impact

COVID-19 Context Questionnaire to assess individual circumstances during pandemic and change in voice experiences.

1, 2, 3

  1. a1 = baseline, 2 = 16 weeks post-randomisation, 3 = 28 weeks post-randomisation