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Table 2 Funding opportunities for independent clinical repurposing research

From: Exploring new uses for existing drugs: innovative mechanisms to fund independent clinical research

Funding source Organisation Name of funding opportunitya Available funds Duration of research Geographic area Disease area
Government organisations Belgian healthcare knowledge center (KCE) (BE) KCE investigator-led trials €10,000,000 per year, no defined max. amount per project Results preferably within 5 years International study possible under certain conditions All
ZonMw (NL) Goed Gebruik Geneesmiddelen – Drug Rediscovery Max. €1,000,000 per call Not specified International study possible if chief investigator and lead institution are NL-based All
National Institute for Health Research (NIHR) and Medical Research Council (MRC) (UK) 19/136 call for evaluating interventions for the diagnosis and treatment of autoimmune diseases Case by case negotiations Not specified International study possible if chief investigator and lead institution are UK-based Autoimmune diseases
Companies Bayer Grants4Indications Case by case negotiations Max. 2 years International All
Not-for-profit organisations CuresWithinReach ReGRoW Pilot US$ 25,000–50,000 per project 12–36 months Low and lower-middle-income-countries (LMICs) Any unsolved disease in LMICs
Michael J. Fox Foundation Therapeutic Pipeline Program US$2,000,000 per project 2–3 years International Parkinson’s disease
The Anticancer Fund (ACF) and Rising Tide Foundation for Clinical Cancer Research (RTFCCR) The RTFCCR/ACF Multi-arm Clinical Trial Award US$ 3,000,000 in total Not specified International Cancer
  1. a Non-exhaustive list of research calls with a focus on drug repurposing between January 2017 and January 2020