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Table 2 Full results from final model

From: Including random centre effects in design, analysis and presentation of multi-centre trials

Covariate

Point estimate

Standard error

95% CI

P value

Treatment (active)

0.89

0.042

0.81 to 0.98

0.014

Time from injury (> 1–3 h)

0.86

0.054

0.76 to 0.97

0.015

Time from injury (> 3 h)

0.75

0.051

0.66 to 0.86

< 0.0001

Age (years)

0.99

0.007

0.98 to 1.01

0.332

Age2

1.00

0.00008

1.00 to 1.00

< 0.0001

SBP (mmHg)

0.93

0.004

0.93 to 0.94

< 0.0001

SBP2

1.00

0.00002

1.00 to 1.00

< 0.0001

GCS (moderate)

0.21

0.015

0.18 to 0.24

< 0.0001

GCS (mild)

0.07

0.004

0.06 to 0.08

< 0.0001

Injury type (penetrating)

0.81

0.054

0.71 to 0.93

0.002

  1. Variance of country intercept: 0.236
  2. Variance of centre intercept (country variance taken into account): 0.409