Variable | Description | Time frame |
---|---|---|
Primary outcome | ||
Physical and functional well-being measured by the FACT-G TOI | Sum of physical and functional well-being subscales of the FACT-G. Higher scores indicate better outcome. | 90 days |
Secondary outcomes | ||
Quality of life measured by the total FACT-G score | Total score of all subscales (physical well-being, social/family well-being, emotional well-being, functional well-being) of the FACT-G. Higher scores indicate better outcome. | 90 days |
Days alive at home without an emergency room visit | Days alive without an emergency room visit and without being an inpatient of a hospital or other healthcare facility. | 90 days |
All-cause mortality | Time to death (in days). | 1 year |
Exploratory outcomes | ||
Anxiety measured by PROMIS Anxiety T-score | T-score calculated from the PROMIS Emotional Distress-Anxiety 6a Short Form. Higher scores indicate more anxiety. | 90 days |
Depression measured by PROMIS Depression T-score | T-score calculated from the PROMIS Depression 6a Short Form. Higher scores indicate more symptoms of depression. | 90 days |
Time to initiation of adjuvant therapy | Time to initiation of adjuvant chemotherapy or radiation (in days). Death will be a competing risk. | 90 days |
Caregiver burden measured by the Short Form Zarit Burden Interview score | Short Form Zarit Burden Interview (ZBI-12) score. Higher scores indicate more caregiver burden. | 90 days |
Size of life space measured by the Life-Space Assessment Questionnaire | Life-Space Assessment Questionnaire score. Higher scores indicate larger life space. | 90 days |