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Table 7 Sequential Organ Failure Assessment (SOFA) Score [20]

From: Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to extended-spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacterales (“MERINO-3”): study protocol for a multicentre, open-label randomised non-inferiority trial

Organ/system

0

1

2

3

4

SpO2/FiO2

> 400

< 400

< 300

< 200 and mechanical ventilation

< 100 and mechanical ventilation

Bilirubin (μmol/L)

< 20

20–32

33–101

102–204

> 204

Hypotension

MAP ≥ 70 mmHg

MAP < 70 mmHg

Dopamine ≤ 5 μ/kg/min or dobutamine any dose

Dopamine > 5, adrenaline ≤ 0.1, noradrenaline ≤ 0.1

Dopamine > 15, adrenaline > 0.1, noradrenaline > 0.1

Platelets (× 109)

≥150

< 150

< 100

< 50

< 20

GCS

15

13–14

10–12

6–9

< 6

Creatinine (mg/dL)

< 1.2

1.2–1.9

2.0–3.4

3.5–4.9

> 5.0