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Table 1 Distribution of patients per cohort

From: Determination of the optimal dose of ephedrine in the treatment of arterial hypotension due to general anesthesia in neonates and infants below 6 months old: the ephedrine study protocol for a randomized, open-label, controlled, dose escalation trial

Dose (mg/kg) 0.1 0.6 0.8 1.0 1.2 1.4
Cohort 1 10 10 0 0 0 0
Cohort 2 5 5 10 0 0 0
Cohort 3 3 3 4 10 0 0
Cohort 4 2 2 3 3 10 0
Cohort 5 2 2 2 2 2 10
Cohort 6 2 2 2 2 5 7
Total 24 24 21 17 17 17