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Table 5 Comparison of changes in outcome measurements between patients who received Dangguixu-san and those who received placebo for grade I acute lateral ankle sprain (n = 23)

From: Effects of Dangguixu-san in patients with acute lateral ankle sprain: a randomized controlled trial

Dependent variables Group (n) Week 0 (M ± SD) Week 1 (M ± SD) Week 5 (M ± SD) Difference (w1–w0) Z (p)a Difference (w5–w0) Z (p)a Difference (w5–w1) Z (p)a
VAS of pain DS (n = 12) 39.33 ± 14.51 19.50 ± 11.70 16.67 ± 21.46 − 19.83 ± 15.02 − 0.31 (0.755) − 22.67 ± 24.64 − 0.56 (0.577) − 2.83 ± 20.66 − 0.32 (0.750)
Placebo (n = 11) 43.91 ± 21.19 22.82 ± 12.24 14.73 ± 10.56 − 21.09 ± 15.00 −29.18 ± 19.81 −8.09 ± 8.62
Degree of edema DS (n = 12) 0.17 ± 0.39 0.17 ± 0.58 0.25 ± 0.45 0.03 ± 0.36 − 0.24 (0.812) 0.03 ± 0.45 − 0.79 (0.431) 0.00 ± 0.67 − 0.69 (0.488)
Placebo (n = 11) 0.09 ± 0.54 0.09 ± 0.30 0.00 ± 0.00 − 0.06 ± 0.24 −0.08 ± 0.25 −0.02 ± 0.26
TOTAL
EQ-5D-5L
DS (n = 12) 9.33 ± 1.78 7.08 ± 1.56 7.50 ± 3.66 − 2.25 ± 1.82 − 0.84 (0.399) − 1.83 ± 3.90 − 0.77 (0.439) 0.42 ± 4.10 − 0.51 (0.609)
Placebo (n = 11) 10.73 ± 2.90 7.73 ± 1.49 7.18 ± 1.89 − 3.00 ± 2.10 − 3.55 ± 3.83 − 0.55 ± 2.62
TOTAL FAOS DS (n = 12) 349.28 ± 60.85 393.40 ± 51.89 403.23 ± 98.09 44.13 ± 52.35 − 0.19 (0.854) 53.95 ± 86.99 − 1.05 (0.295) 9.83 ± 100.83 − 0.86 (0.389)
placebo (n = 11) 314.15 ± 88.63 376.45 ± 62.75 410.71 ± 63.41 62.31 ± 84.87 96.56 ± 106.41 34.25 ± 60.46
  1. aMann-Whitney U test