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Table 1 Inclusion and exclusion criteria

From: Blended cognitive behaviour therapy for children and adolescents with mitochondrial disease targeting fatigue (PowerMe): study protocol for a multiple baseline single case experiment

Inclusion criteria Exclusion criteria
- Age between 8 and 18 years
- Able to speak, write, and read Dutch
- Diagnosed with mitochondrial disease (genetically confirmed)
- Being severely fatigued (CIS fatigue severity ≥35)
- Access to a computer with internet connection
- Basic computer skills
- Able to travel to the hospital for the CBT intervention (3 sessions)
- Intellectual disability (developmental age younger than 8 years).
- Primary depression (CDI ≥16) or anxiety disorder (SCARED-C ≥ 25)
- Current psychological treatment for fatigue