Table 1 PRECIS-2 ratings to demonstrate the extent of pragmatism in the trial design immediately following the pilot study
Domain | Scorea | Rational |
|---|---|---|
Eligibility criteria | 4 | All patients with opioid-related issues are study eligible except those who are not able to provide informed consent by the time of ED discharge. |
Recruitment path | 5 | Patients are recruited when they are present in the ED or on an inpatient unit if they were admitted there from the ED. |
Setting | 4 | The trial is occurring in university-affiliated teaching hospitals; however, the specific EDs do not regularly engage in research. |
Organization intervention | 3 | The research grant provides the hospital with funding and resources to implement and run the intervention; however, the hospital employs and supervises PRCs. |
Flex of experimental intervention delivery | 3 | PRCs are given guidelines for how to engage patients, but implementation of guidelines is not regularly monitored. |
Flex of experimental intervention adherence | 5 | Patients are not expected to adhere to the intervention; rather, it is up to the PRCs to engage and motivate them. |
Follow-up | 5 | All follow-up data collection is through existing administrative sources. |
Outcome | 5 | Primary outcomes are (1) treatment linkage, (2) treatment engagement, (3) reduced overdose, and (4) reduced overdose mortality, which are all relevant to people in OUD recovery. |
Analysis | 5 | An intention-to-treat approach is followed. |