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Table 1 Time schedule of enrolment, intervention, assessments, and study visits for participants

From: Efficacy of metformin and fermentable fiber combination therapy in adolescents with severe obesity and insulin resistance: study protocol for a double-blind randomized controlled trial

  1. Abbreviations: ALT alanine aminotransferase, AST aspartate transaminase, BUN blood urea nitrogen, CBC-D complete blood count with differential, GLP-1 glucagon-like peptide 1, HbA1c hemoglobin A1C, HOMA-IR homeostatic model assessment of insulin resistance, CRP C-reactive protein, IL-6 Interleukin 6, LBP lipopolysaccharide-binding protein, PYY peptide tyrosine tyrosine, SLIM satiety labeled intensity magnitude, TMAO trimethylamine N-oxide, TNF-α tumor necrosis factor alpha, TSH thyroid-stimulating hormone