Can hypnosis and virtual reality reduce anxiety, pain and fatigue among patients who undergo cardiac surgery: a randomised controlled trial

Table 2 Standard Protocol Items: Recommendation for Interventional Trials (SPIRIT) study schedule

Timepoint	Study period
	Hospital admission (Day − 1)		Surgery (Day 0)	Intensive care unit admission (Day + 1)
	T0	T1		T2	T3
Enrolment
Eligibility screen	X
Informed consent	X
Allocation
Control, hypnosis, virtual reality, virtual reality hypnosis	X
Assessments
Baseline: demographic factors, Dissociative Experience Scale [58]	X
Primary outcome: anxiety	X	X		X	X
Secondary variables: pain, fatigue, relaxation, heart rate, arterial pressure, respiratory rate, oxygen saturation, pupil size	X	X		X	X
Phenomenology scales: absorption, dissociation, immersion, presence, time perception		X			X
Nurse’s and patient’s interview		X			X

ISSN: 1745-6215