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Table 3 Study design and top three most commonly reported outcome categories

From: Outcome reporting in neonates experiencing withdrawal following opioid exposure in pregnancy: a systematic review

Type of study

First most commonly reported outcome category

Second most commonly reported outcome category(ies)

Third most commonly reported outcome category(ies)

Retrospective cohort study (n = 21)

Duration of hospital stay (16%)

NAS symptoms (13%)

Duration of pharmacotherapy (12%)

Randomized controlled trial (n = 10)

Duration of pharmacotherapy (22%)

Duration of hospital stay (12%)

Adjunctive therapy (10%)

Adverse events (10%)

Prospective cohort study (n = 5)

Dose of pharmacotherapy (22%)

Duration of pharmacotherapy (17%)

Duration of hospital stay (11%)

NAS symptoms (11%)

Initiation of pharmacotherapy (11%)

Quality improvement (n = 4)

Duration of hospital stay (15%)

Adverse events (12%)

Initiation of pharmacotherapy (8%)

Cost of treatment (12%)

Readmission to hospital (8%)

Advancing level of care (NICU admission) (12%)

Feeding breast milk (8%)

Custody at discharge (8%)

Case series and case report (n = 4)

Miscellaneous single outcomes (25%)

Duration of pharmacotherapy (17%)

Duration of hospital stay (8%)

NAS symptoms (17%)

Dose of pharmacotherapy (8%)

Adverse events (17%)

Adjunctive therapy (8%)

Qualitative study (n = 1)

NAS symptoms (100%)

  

Mixed method (n = 1)

Feeding breast milk (100%)

NAS symptoms (25%)

 

Initiation of pharmacotherapy (25%)

 

Prospective within-subject study(n = 1)

Miscellaneous single outcomes (100%)

  
  1. NAS neonatal abstinence syndrome