Study protocol for a randomized controlled trial: prophylactic swallowing exercises in head-and-neck cancer patients treated with (chemo)radiotherapy (PRESTO trial)

Table 1 Study visits and evaluations

			Study period
	Enrollment	Allocation	Post allocation
Time point	Pre RT	Between enrollment and start RT	Weeks 1–4 of RT	Weeks 5–7 of RT	End of RT	1 month after RT	3 months after RT
Enrollment:
Eligibility screen	X
Informed consent	X
Allocation		X
Interventions:
PSE – control group			X
PSE – app group			X
PSE – therapist group			X
Assessments:
Patient, disease and therapy characteristics	X
Swallowing function	X		X		X	X	X
Muscle strength	X		X		X	X	X
Impact of mucositis	X		X		X	X	X
Quality of life	X				X	X	X
Attitudes towards exercises			X
Overall fatigue	X		X

ISSN: 1745-6215