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Table 6 Basic information for the three example trials

From: A simulation study comparing the power of nine tests of the treatment effect in randomized controlled trials with a time-to-event outcome

 

Trial

 

PATCH1

UKCTOCS

RE01

Outcome (time to)

Recurrence

Ovarian cancer death

Death (any cause)

Research arm

Penicillin

Screening

Interferon- α

Control arm

Placebo

No screening

MPA

Type of treatment effect

Early

Late

PH

Event rate

Low/medium

Low

High

n

274

202,546

347

Events

129

649

322

Smin

0.419

0.996

0.045