A simulation study comparing the power of nine tests of the treatment effect in randomized controlled trials with a time-to-event outcome

Table 5 Summary of findings from our simulation studies

Effect	Acceptable tests (mean deficits over low and high event rates)
Early	SupLR (0.011), C (0.015), VWLR2 (0.022), J (0.030), LRE (0.040), WC (0.041)
Late	LRL (0.004), VWLR (0.008), VWLR2 (0.013), WC (0.014), J (0.021)
PH	LR (0.000), LRE (0.018), VWLR (0.021), C (0.027), VWLR2 (0.029), SupLR (0.038)

Acceptable tests for different presumed types of treatment effects in increasing order of their mean power deficits. See text for details

ISSN: 1745-6215