Inclusion criteria | Exclusion criteria |
---|---|
To be included women had to: | Women were excluded if they: |
Be aged ≥18 years at the time of recruitment | Had a positive diagnosis of HIV/AIDS, syphilis, psychosis, diabetes before or during pregnancy, thyroid disease or any disorder causing vitamin D hypersensitivity (e.g. sarcoidosis and other lymphomatous disorders) |
Be up to 20 weeks’ gestation at 1st prenatal visit | Had lactose intolerance, milk allergy, history of kidney stones or family history of kidney stones or hyperparathyroidism |
Have a positive diagnosis of periodontitis (≥ 1 tooth with at least one site with equal or more than 4 mm of clinical attachment loss [CAL] and presence of bleeding on probing); and | Were being prescribed or using antibiotics or any immune suppressants or medication affecting vitamin D/calcium metabolism or had drug or alcohol abuse |
Be cognitively and physically able to complete an interview and oral examination and willing to participate, including providing blood samples | Reported consumption of equal or more than 4 servings per day of dairy products or taking vitamin D supplements more than 400 IU/day |
Had extensive dental decay (crowns of several teeth destroyed by caries) or use of fixed dental braces |