Table 3 Simulation method 3a.. Estimates (percent bias) of effect (difference at the fourth time point) and variance components, where k = number of clusters per arm and m = cluster size
k | m | ICC = 0.01 | ICC = 0.1 | ||||||
|---|---|---|---|---|---|---|---|---|---|
effect = 5 | \( {\sigma}_c^2=0.71 \) | \( {\sigma}_w^2=39 \) | \( {\sigma}_b^2=60 \) | effect = 5 | \( {\sigma}_c^2=7.14 \) | \( {\sigma}_w^2=30 \) | \( {\sigma}_b^2=60 \) | ||
5 | 10 | 5.03 (0.6) | 2.0 (186.0) | 39.6 (1.6) | 58.9 (− 1.8) | 4.99 (− 0.1) | 8.2 (15.1) | 32.4 (7.9) | 59.7 (− 0.5) |
20 | 5.00 (0.1) | 1.3 (76.6) | 39.3 (0.7) | 59.4 (− 1.0) | 4.97 (− 0.6) | 7.8 (9.0) | 32.2 (7.4) | 59.7 (− 0.5) | |
50 | 4.95 (− 1.1) | 0.8 (18.0) | 39.2 (0.5) | 60.0 (− 0.1) | 4.97 (− 0.5) | 8.0 (11.8) | 32.3 (7.6) | 59.5 (− 0.8) | |
10 | 10 | 5.03 (0.6) | 1.7 (132.2) | 39.2 (0.5) | 59.1 (− 1.4) | 4.98 (− 0.5) | 8.0 (12.5) | 32.7 (8.9) | 58.9 (− 1.8) |
20 | 5.03 (0.5) | 1.0 (43.7) | 39.3 (0.7) | 59.7 (− 0.5) | 4.93 (− 1.4) | 7.8 (9.2) | 32.5 (8.4) | 59.2 (− 1.4) | |
50 | 4.96 (− 0.7) | 0.8 (17.5) | 39.3 (0.7) | 59.7 (− 0.4) | 5.12 (2.4) | 7.8 (8.9) | 32.5 (8.4) | 59.3 (− 1.1) | |
20 | 10 | 4.98 (− 0.4) | 1.2 (72.9) | 39.3 (0.8) | 59.5 (− 0.8) | 5.04 (0.8) | 7.8 (9.7) | 32.8 (9.2) | 59.5 (− 0.8) |
20 | 5.00 (0.0) | 0.9 (26.5) | 39.3 (0.8) | 59.9 (− 0.2) | 5.03 (0.6) | 7.8 (9.2) | 32.7 (9.0) | 59.4 (− 1.1) | |
50 | 5.01 (0.1) | 0.8 (11.2) | 39.3 (0.7) | 60.0 (− 0.1) | 4.95 (− 1.0) | 7.9 (10.4) | 32.7 (9.1) | 59.4 (− 1.0) | |
50 | 10 | 5.00 (0.1) | 0.9 (28.1) | 39.3 (0.8) | 59.7 (− 0.6) | 4.98 (− 0.5) | 7.8 (9.8) | 32.8 (9.2) | 59.3 (− 1.1) |
20 | 4.98 (− 0.5) | 0.8 (10.1) | 39.2 (0.6) | 59.9 (− 0.1) | 5.02 (0.4) | 7.9 (10.5) | 32.8 (9.4) | 59.4 (− 1.1) | |