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Table 1 Titration administration, including dose and number of sprays

From: Use of cannabinoid-based medicine among older residential care recipients diagnosed with dementia: study protocol for a double-blind randomised crossover trial

Day(s)

Week

Dose administered (daily)

Number of spray(s) per dose

Adverse events recorded (time)

9 am

2 pm

1, 2

1

–

2.5 mg

1

3 pm

3, 4

1

2.5

2.5

1

 

5, 6

1

2.5

5

1–2

3 pm

7, 8

1

5

5

2

 

9, 10

2

5

10

2–4

3 pm

11, 12

2

10

10

4

 

13, 14

2

10

15

4–6

3 pm

15, 16

2/3

15

15

6

 

17, 18

3

15

20

6–8

3 pm

19, 20

3

20

20

8

 

21, 22

3/4

20

25

8–10

3 pm

23, 24

4

25

25

10

3 pm

  1. Adverse events will be recorded 1 h after drug administration on days of dose increase (days bolded) and on the last day of the treatment period
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Trials

ISSN: 1745-6215