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Table 1 FWER, sample size, critical value (CV) and overall power comparisons for 90% marginal power

From: Designs for adding a treatment arm to an ongoing clinical trial

DesignFWERTotal sample sizeCVOverall power
Two separate trials0.04949361.960.81
Two separate trials: adjustment for multiplicity0.025011042.240.81
Single trial: no multiplicity adjustment0.04547021.960.83
Single trial: Dunnett adjustment for multiplicity0.02508162.210.83
Adding an arm: no multiplicity adjustment0.04778021.960.82
Adding an arm: Dunnett adjustment for multiplicity0.02509222.230.82