Strategy for addressing research-site overlap in pragmatic clinical trials: lessons learned from the NIH-DOD-VA Pain Management Collaboratory (PMC)

Table 4 Remediation strategies for Military Treatment Facilities (MTFs) in the Pain Management Collaboratory (PMC)

MTF	Remediation plan
Brooke Army, San Antonio, TX	PMC #5	• Coordinate site-recruitment efforts by communicating locations and avoiding clinics with PMC #9. • Coordinate site-recruitment efforts by communicating locations of clinics to PMC #11.
	PMC #9	• Coordinate site-recruitment efforts by communicating locations and avoiding clinics with PMC #5. • Coordinate site-recruitment efforts at site by communicating locations of clinics to PMC #11.
	PMC #10	• Exclude patients with chronic pain > 3 months of any severity or anatomic location.
	PMC #11	• Coordinate site-recruitment efforts by avoiding clinics being used by PMC #5. • Coordinate site-recruitment efforts by avoiding clinics being used by PMC #9.
Navy Medical, San Diego, CA	PMC #10	• Exclude patients with chronic pain > 3 months of any severity or anatomic location.
Navy Medical, San Diego, CA	PMC #11	• No action required.
Walter Reed, Bethesda, MD	PMC #9	• Avoid—do not recruit at this site.
	PMC #10	• Exclude patients with chronic pain > 3 months of any severity or anatomic location.
	PMC #11	• No action required.
Darnall, Fort Hood, TX	PMC #5	• Coordinate site-recruitment efforts by communicating locations and avoiding clinics with PMC #9.
Wilford Hall, San Antonio, TX	PMC #9	• Coordinate site-recruitment efforts by communicating locations and avoiding clinics with PMC #5.

ISSN: 1745-6215