TY - JOUR AU - Piel, F. B. AU - Hay, S. I. AU - Gupta, S. AU - Weatherall, D. J. AU - Williams, T. N. PY - 2013 DA - 2013// TI - Global burden of sickle cell anaemia in children under five, 2010-2050: modelling based on demographics, excess mortality, and interventions JO - PLoS Med VL - 10 UR - https://doi.org/10.1371/journal.pmed.1001484 DO - 10.1371/journal.pmed.1001484 ID - Piel2013 ER - TY - JOUR AU - Piel, F. B. AU - Patil, A. P. AU - Howes, R. E. PY - 2013 DA - 2013// TI - Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates JO - Lancet VL - 381 UR - https://doi.org/10.1016/S0140-6736(12)61229-X DO - 10.1016/S0140-6736(12)61229-X ID - Piel2013 ER - TY - JOUR AU - Hassell, K. L. PY - 2010 DA - 2010// TI - Population estimates of sickle cell disease in the U.S JO - Am J Prev Med VL - 38 UR - https://doi.org/10.1016/j.amepre.2009.12.022 DO - 10.1016/j.amepre.2009.12.022 ID - Hassell2010 ER - TY - JOUR AU - Gill, F. M. AU - Sleeper, L. A. AU - Weiner, S. J. PY - 1995 DA - 1995// TI - Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative Study of Sickle Cell Disease JO - Blood VL - 86 UR - https://doi.org/10.1182/blood.V86.2.776.bloodjournal862776 DO - 10.1182/blood.V86.2.776.bloodjournal862776 ID - Gill1995 ER - TY - JOUR AU - Ohene-Frempong, K. AU - Weiner, S. J. AU - Sleeper, L. A. PY - 1998 DA - 1998// TI - Cerebrovascular accidents in sickle cell disease: rates and risk factors JO - Blood VL - 91 ID - Ohene-Frempong1998 ER - TY - JOUR AU - Marcus, S. J. AU - Ware, R. E. PY - 1999 DA - 1999// TI - Physiologic decline in fetal hemoglobin parameters in infants with sickle cell disease: implications for pharmacological intervention JO - J Pediatr Hematol Oncol VL - 21 UR - https://doi.org/10.1097/00043426-199909000-00013 DO - 10.1097/00043426-199909000-00013 ID - Marcus1999 ER - TY - JOUR AU - Brousse, V. AU - Buffet, P. AU - Rees, D. PY - 2014 DA - 2014// TI - The spleen and sickle cell disease: the sick(led) spleen JO - Br J Haematol VL - 166 UR - https://doi.org/10.1111/bjh.12950 DO - 10.1111/bjh.12950 ID - Brousse2014 ER - TY - JOUR AU - Quinn, C. T. PY - 2013 DA - 2013// TI - Sickle cell disease in childhood: from newborn screening through transition to adult medical care JO - Pediatr Clin N Am VL - 60 UR - https://doi.org/10.1016/j.pcl.2013.09.006 DO - 10.1016/j.pcl.2013.09.006 ID - Quinn2013 ER - TY - JOUR AU - Platt, O. S. PY - 2008 DA - 2008// TI - Hydroxyurea for the treatment of sickle cell anemia JO - N Engl J Med VL - 358 UR - https://doi.org/10.1056/NEJMct0708272 DO - 10.1056/NEJMct0708272 ID - Platt2008 ER - TY - JOUR AU - Charache, S. AU - Terrin, M. L. AU - Moore, R. D. PY - 1995 DA - 1995// TI - Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia JO - N Engl J Med VL - 332 UR - https://doi.org/10.1056/NEJM199505183322001 DO - 10.1056/NEJM199505183322001 ID - Charache1995 ER - TY - JOUR AU - Strouse, J. J. AU - Heeney, M. M. PY - 2012 DA - 2012// TI - Hydroxyurea for the treatment of sickle cell disease: efficacy, barriers, toxicity, and management in children JO - Pediatr Blood Cancer VL - 59 UR - https://doi.org/10.1002/pbc.24178 DO - 10.1002/pbc.24178 ID - Strouse2012 ER - TY - JOUR AU - Lanzkron, S. AU - Strouse, J. J. AU - Wilson, R. PY - 2008 DA - 2008// TI - Systematic review: Hydroxyurea for the treatment of adults with sickle cell disease JO - Ann Intern Med VL - 148 UR - https://doi.org/10.7326/0003-4819-148-12-200806170-00221 DO - 10.7326/0003-4819-148-12-200806170-00221 ID - Lanzkron2008 ER - TY - JOUR AU - Steinberg, M. H. AU - McCarthy, W. F. AU - Castro, O. PY - 2010 DA - 2010// TI - The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: a 17.5 year follow-up JO - Am J Hematol VL - 85 ID - Steinberg2010 ER - TY - JOUR AU - Le, P. Q. AU - Gulbis, B. AU - Dedeken, L. PY - 2015 DA - 2015// TI - Survival among children and adults with sickle cell disease in Belgium: benefit from hydroxyurea treatment JO - Pediatr Blood Cancer VL - 62 UR - https://doi.org/10.1002/pbc.25608 DO - 10.1002/pbc.25608 ID - Le2015 ER - TY - JOUR AU - Voskaridou, E. AU - Christoulas, D. AU - Bilalis, A. PY - 2010 DA - 2010// TI - The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS) JO - Blood VL - 115 UR - https://doi.org/10.1182/blood-2009-05-221333 DO - 10.1182/blood-2009-05-221333 ID - Voskaridou2010 ER - TY - JOUR AU - Lobo, C. L. AU - Pinto, J. F. AU - Nascimento, E. M. AU - Moura, P. G. AU - Cardoso, G. P. AU - Hankins, J. S. PY - 2013 DA - 2013// TI - The effect of hydroxcarbamide therapy on survival of children with sickle cell disease JO - Br J Haematol VL - 161 UR - https://doi.org/10.1111/bjh.12323 DO - 10.1111/bjh.12323 ID - Lobo2013 ER - TY - JOUR AU - McGann, P. T. AU - Ware, R. E. PY - 2011 DA - 2011// TI - Hydroxyurea for sickle cell anemia: what have we learned and what questions still remain? JO - Curr Opin Hematol VL - 18 UR - https://doi.org/10.1097/MOH.0b013e32834521dd DO - 10.1097/MOH.0b013e32834521dd ID - McGann2011 ER - TY - JOUR AU - Yawn, B. P. AU - Buchanan, G. R. AU - Afenyi-Annan, A. N. PY - 2014 DA - 2014// TI - Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members JO - JAMA VL - 312 UR - https://doi.org/10.1001/jama.2014.10517 DO - 10.1001/jama.2014.10517 ID - Yawn2014 ER - TY - JOUR AU - Schuchard, S. B. AU - Lissick, J. R. AU - Nickel, A. PY - 2019 DA - 2019// TI - Hydroxyurea use in young infants with sickle cell disease JO - Pediatr Blood Cancer VL - 66 UR - https://doi.org/10.1002/pbc.27650 DO - 10.1002/pbc.27650 ID - Schuchard2019 ER - TY - JOUR AU - Brousseau, D. C. AU - Richardson, T. AU - Hall, M. PY - 2019 DA - 2019// TI - Hydroxyurea use for sickle cell disease among Medicaid-enrolled children JO - Pediatrics VL - 144 UR - https://doi.org/10.1542/peds.2018-3285 DO - 10.1542/peds.2018-3285 ID - Brousseau2019 ER - TY - JOUR AU - Su, Z. T. AU - Segal, J. B. AU - Lanzkron, S. AU - Ogunsile, F. J. PY - 2019 DA - 2019// TI - National trends in hydroxyurea and opioid prescribing for sickle cell disease by office-based physicians in the United States, 1997-2017 JO - Pharmacoepidemiol Drug Saf VL - 28 UR - https://doi.org/10.1002/pds.4860 DO - 10.1002/pds.4860 ID - Su2019 ER - TY - JOUR AU - Ware, R. E. PY - 2015 DA - 2015// TI - Optimizing hydroxyurea therapy for sickle cell anemia JO - Hematol Am Soc Hematol Educ Program VL - 2015 UR - https://doi.org/10.1182/asheducation.V2015.1.436.3917688 DO - 10.1182/asheducation.V2015.1.436.3917688 ID - Ware2015 ER - TY - JOUR AU - Ware, R. E. AU - Despotovic, J. M. AU - Mortier, N. A. PY - 2011 DA - 2011// TI - Pharmacokinetics, pharmacodynamics, and pharmacogenetics of hydroxyurea treatment for children with sickle cell anemia JO - Blood VL - 118 UR - https://doi.org/10.1182/blood-2011-07-364190 DO - 10.1182/blood-2011-07-364190 ID - Ware2011 ER - TY - JOUR AU - Paule, I. AU - Sassi, H. AU - Habibi, A. PY - 2011 DA - 2011// TI - Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen JO - Orphanet J Rare Dis VL - 6 UR - https://doi.org/10.1186/1750-1172-6-30 DO - 10.1186/1750-1172-6-30 ID - Paule2011 ER - TY - JOUR AU - Alvarez, O. AU - Miller, S. T. AU - Wang, W. C. PY - 2012 DA - 2012// TI - Effect of hydroxyurea treatment on renal function parameters: results from the multi-center placebo-controlled BABY HUG clinical trial for infants with sickle cell anemia JO - Pediatr Blood Cancer VL - 59 UR - https://doi.org/10.1002/pbc.24100 DO - 10.1002/pbc.24100 ID - Alvarez2012 ER - TY - JOUR AU - Ware, R. E. AU - Rees, R. C. AU - Sarnaik, S. A. PY - 2010 DA - 2010// TI - Renal function in infants with sickle cell anemia: baseline data from the BABY HUG trial JO - J Pediatr VL - 156 UR - https://doi.org/10.1016/j.jpeds.2009.06.060 DO - 10.1016/j.jpeds.2009.06.060 ID - Ware2010 ER - TY - JOUR AU - Steinberg, M. H. AU - Chui, D. H. AU - Dover, G. J. AU - Sebastiani, P. AU - Alsultan, A. PY - 2014 DA - 2014// TI - Fetal hemoglobin in sickle cell anemia: a glass half full? JO - Blood VL - 123 UR - https://doi.org/10.1182/blood-2013-09-528067 DO - 10.1182/blood-2013-09-528067 ID - Steinberg2014 ER - TY - JOUR AU - Buchanan, G. R. PY - 2014 DA - 2014// TI - “Packaging” of fetal hemoglobin in sickle cell anemia JO - Blood VL - 123 UR - https://doi.org/10.1182/blood-2013-11-539981 DO - 10.1182/blood-2013-11-539981 ID - Buchanan2014 ER - TY - JOUR AU - McGann, P. T. AU - Niss, O. AU - Dong, M. PY - 2019 DA - 2019// TI - Robust clinical and laboratory response to hydroxyurea using pharmacokinetically guided dosing for young children with sickle cell anemia JO - Am J Hematol VL - 94 UR - https://doi.org/10.1002/ajh.25510 DO - 10.1002/ajh.25510 ID - McGann2019 ER - TY - JOUR AU - Shook, L. M. AU - Farrell, C. B. AU - Kalinyak, K. A. PY - 2016 DA - 2016// TI - Translating sickle cell guidelines into practice for primary care providers with Project ECHO JO - Med Educ Online VL - 21 UR - https://doi.org/10.3402/meo.v21.33616 DO - 10.3402/meo.v21.33616 ID - Shook2016 ER - TY - JOUR AU - Dong, M. AU - McGann, P. T. AU - Mizuno, T. AU - Ware, R. E. AU - Vinks, A. A. PY - 2016 DA - 2016// TI - Development of a pharmacokinetic-guided dose individualization strategy for hydroxyurea treatment in children with sickle cell anaemia JO - Br J Clin Pharmacol VL - 81 UR - https://doi.org/10.1111/bcp.12851 DO - 10.1111/bcp.12851 ID - Dong2016 ER - TY - JOUR AU - Marahatta, A. AU - Ware, R. E. PY - 2017 DA - 2017// TI - Hydroxyurea: analytical techniques and quantitative analysis JO - Blood Cells Mol Dis VL - 67 UR - https://doi.org/10.1016/j.bcmd.2017.08.009 DO - 10.1016/j.bcmd.2017.08.009 ID - Marahatta2017 ER - TY - JOUR AU - Heeney, M. M. AU - Whorton, M. R. AU - Howard, T. A. AU - Johnson, C. A. AU - Ware, R. E. PY - 2004 DA - 2004// TI - Chemical and functional analysis of hydroxyurea oral solutions JO - J Pediatr Hematol Oncol VL - 26 UR - https://doi.org/10.1097/00043426-200403000-00007 DO - 10.1097/00043426-200403000-00007 ID - Heeney2004 ER - TY - JOUR AU - Fabricius, E. AU - Rajewsky, F. PY - 1971 DA - 1971// TI - Determination of hydroxyurea in mammalian tissues and blood JO - Rev Eur Etud Clin Biol VL - 16 ID - Fabricius1971 ER - TY - JOUR AU - Marahatta, A. AU - Megaraj, V. AU - McGann, P. T. AU - Ware, R. E. AU - Setchell, K. D. PY - 2016 DA - 2016// TI - Stable-isotope dilution HPLC-electrospray ionization tandem mass spectrometry method for quantifying hydroxyurea in dried blood samples JO - Clin Chem VL - 62 UR - https://doi.org/10.1373/clinchem.2016.263715 DO - 10.1373/clinchem.2016.263715 ID - Marahatta2016 ER - TY - JOUR AU - Proost, J. H. AU - Meijer, D. K. PY - 1992 DA - 1992// TI - MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring JO - Comput Biol Med VL - 22 UR - https://doi.org/10.1016/0010-4825(92)90011-B DO - 10.1016/0010-4825(92)90011-B ID - Proost1992 ER - TY - JOUR AU - Ware, R. E. AU - Helms, R. W. AU - Investigators, S. W. PY - 2012 DA - 2012// TI - Stroke with transfusions changing to hydroxyurea (SWiTCH) JO - Blood VL - 119 UR - https://doi.org/10.1182/blood-2011-11-392340 DO - 10.1182/blood-2011-11-392340 ID - Ware2012 ER - TY - JOUR AU - Harris, P. A. AU - Taylor, R. AU - Minor, B. L. PY - 2019 DA - 2019// TI - The REDCap consortium: Building an international community of software platform partners JO - J Biomed Inform VL - 95 UR - https://doi.org/10.1016/j.jbi.2019.103208 DO - 10.1016/j.jbi.2019.103208 ID - Harris2019 ER - TY - JOUR AU - Harris, P. A. AU - Taylor, R. AU - Thielke, R. AU - Payne, J. AU - Gonzalez, N. AU - Conde, J. G. PY - 2009 DA - 2009// TI - Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support JO - J Biomed Inform VL - 42 UR - https://doi.org/10.1016/j.jbi.2008.08.010 DO - 10.1016/j.jbi.2008.08.010 ID - Harris2009 ER - TY - JOUR AU - Wang, W. C. AU - Ware, R. E. AU - Miller, S. T. PY - 2011 DA - 2011// TI - Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG) JO - Lancet VL - 377 UR - https://doi.org/10.1016/S0140-6736(11)60355-3 DO - 10.1016/S0140-6736(11)60355-3 ID - Wang2011 ER -