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Table 2 Pathogen-specific point-of-care (POC) tests

From: Impact of a package of diagnostic tools, clinical algorithm, and training and communication on outpatient acute fever case management in low- and middle-income countries: protocol for a randomized controlled trial

Pathogen

Type of test

Dengue virus

Lateral flow RDT: detects Dengue virus NS1 antigen and IgM (and IgG) from serum or whole blood

Streptococcus pyogenes

Lateral flow RDT: detects group A streptococcal antigen from throat swabs

Salmonella enterica serovar Typhi

Lateral flow RDT: detects Salmonella typhi-specific IgM from serum or whole blood

Orientia tsutsugamushi (scrub typhus)

Lateral flow RDT: detects Orientia tsutsugamushi antibodies (IgG, IgM, and IgA) in human serum, plasma, whole blood

Influenza virus

Lateral flow RDT: detects influenza virus type A, type B and A(H1N1) pandemic antigens directly from nasal/throat/nasopharyngeal swab or nasal/nasopharyngeal aspirate

Chikungunya virus

Lateral flow RDT: detects Chikungunya virus IgG/IgM antibodies in serum, plasma or whole blood

Streptococcus pneumoniae

Lateral flow RDT: detects S. pneumoniae antigen in the urine of patients with pneumococcal pneumonia

Respiratory syncytial virus

Lateral flow RDT: detects respiratory syncytial virus (RSV) fusion protein antigen in nasal wash and nasopharyngeal (NP) swab specimens

Leptospira interrogans (leptospirosis)

Lateral flow RDT: detects Leptospira interrogans IgM antibodies from urine

Plasmodium Sp. (malaria)

Lateral flow RDT as per national guidelines