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Table 1 Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) schedule of the trial

From: Acupuncture for chronic persistent asthma based on the theory of Meridian-viscera Association: study protocol for a multi-center randomized controlled trial in China

  1. This is a randomized controlled trial which includes a 2-week baseline period, a 4-week treatment period, and an 8-week follow-up period. In the baseline period, recruited patients will be screened, and eligible asthma patients will sign an informed consent and receive a physical examination. After allocation, the patients will receive 12 sessions of acupuncture (acupoint of Lung meridian or Heart meridian) during the treatment period. The outcome assessments, AQLQ, and ACT are performed at baseline, at the end of treatment, during the follow-up, and at the end of the follow-up. The outcome assessments, PEF, FEV1, SAS, and SDS are performed at baseline and at the end of treatment. In addition, the asthma dairy should be recorded at any time during the trial if asthma attacks. The first time of emergency medicine taken should be recorded at any time during the follow-up period. The expectation of acupuncture will be assessed at baseline. The physical examination including blood routine test and blood biochemical test will also be performed at the end of treatment to evaluate risks correlated with acupuncture. Adverse events will be recorded at any time during treatment
  2. AQLQ Asthma Quality of Life Questionnaire, ACT Asthma Control Test, PEF Peak Expiratory Flow, FEV1 Forced Expiratory Volume in 1 s, SAS Self-rating Anxiety Scale, SDS Self-rating Depression Scale, EM Emergency Medicine