Therapeutic scheme before the washout period | Therapeutic replacement scheme | Washout period |
---|---|---|
No use of inhaled medication | Maintain the original treatment | Go directly into randomization without washout |
SABA on demand | ||
Budesonide/formoterol (160 μg/4.5 μg/dose, 1–2 doses/time, b.i.d.) | ||
Regular inhalation of SABA and/or LABA and/or ICS and/or anticholinergics and/or other types/doses of inhaled drugs | Budesonide/formoterol (160 μg/4.5 μg/dose, 1–2 doses/time, b.i.d.) | For 4 weeks |