|
Control group
|
Intervention group
|
---|
n
|
Baseline
|
Follow-up
|
n
|
Baseline
|
Follow-up
|
---|
Pre-test
|
ACTH*, pmol/L
|
40
|
4.6 (3.8; 5.6)
|
5.8 (4.8; 7.0)
|
45
|
6.1 (5.1; 7.2)
|
7.0 (6.2; 7.9)
|
Cortisol*, nmol/L
|
38
|
233 (204; 265)
|
254 (221; 293)
|
44
|
242 (224; 262)
|
277 (255; 305)
|
SBP, mmHg
|
40
|
129 (123; 134)
|
130 (124; 135)
|
46
|
128 (123; 133)
|
129 (125; 133)
|
DBP, mmHg
|
40
|
78 (74; 81)
|
77 (74; 81)
|
46
|
74 (70; 77)
|
75 (73; 78)
|
HR, bpm
|
38
|
73 (70; 76)
|
79 (76; 83)
|
44
|
71 (68; 74)
|
78 (76; 80)
|
Peak
|
ACTH*, pmol/L
|
40
|
13.0 (10.2; 16.8)
|
10.6 (8.4; 13.5)
|
47
|
15.6 (13.0; 18.7)
|
12.6 (10.8; 14.7)
|
Cortisol, nmol/L
|
40
|
450 (406; 493)
|
439 (398; 480)
|
45
|
468 (436; 501)
|
456 (426; 486)
|
SBP, mmHg
|
39
|
171 (162; 180)
|
163 (156; 170)
|
46
|
164 (158; 171)
|
158 (151; 164)
|
DBP, mmHg
|
39
|
104 (100; 109)
|
101 (97; 105)
|
46
|
99 (95; 102)
|
97 (94; 100)
|
HR*, bpm
|
38
|
101 (95; 108)
|
94 (87; 99)
|
46
|
97 (92; 104)
|
95 (90; 99)
|
Lowest value
|
ACTH*, pmol/L
|
40
|
3.5 (3.0; 4.0)
|
3.7 (3.2; 4.3)
|
47
|
3.9 (3.5; 4.4)
|
4.1 (3.6; 4.6)
|
Cortisol, nmol/L
|
40
|
301 (267; 334)
|
271 (241; 301)
|
45
|
302 (272; 331)
|
278 (256; 298)
|
SBP, mmHg
|
36
|
120 (115; 125)
|
118 (113; 123)
|
44
|
118 (115; 122)
|
118 (114; 122)
|
DBP, mmHg
|
36
|
72 (68; 75)
|
67 (65; 72)
|
44
|
68 (65; 70)
|
66 (64; 69)
|
HR, bpm
|
36
|
64 (61; 67)
|
63 (60; 65)
|
44
|
63 (60; 65)
|
61 (58; 63)
|
- *Geometric mean and anti-logged 95% confidence intervals (CI)
- ACTH adrenocorticotropic hormone, SBP systolic blood pressure, DBT diastolic blood pressure, HR heart rate, Bpm beats per minute