Prior to start of clinical study | Enrollment | Within 12 months of enrollment | Within 12–24 months of enrollment | Within 24–36 months of enrollment | Within 36–48 months of enrollment (possible 3rd season) | |
---|---|---|---|---|---|---|
Enrollment (year 1) | ||||||
Cluster eligibility screen | X | |||||
Individual eligibility screen | X | |||||
Informed consent | X | |||||
Allocation | X | |||||
Interventions* (years 2–3) | ||||||
TIRS1 | X | |||||
TIRS2 | X | |||||
TIRS3 | X | |||||
No activities in untreated clusters | X | X | X | |||
Assessments | ||||||
Baseline: entomology, seroprevalence | X | |||||
Active surveillance/entomology | X | X | X | |||
Annual sero-survey | X | X | X | |||
Mobility surveys | X | X | X | X | ||
Monitoring insecticide adverse effects | X | X | X | |||
Laboratory testing | X | X | X | X |